Curriculum Vitae

Personal information
First name / Surname
Krisztián Papp
E-mail
info@abc-arrays.com
Date of birth
1980
Gender
Male
Work experience
Dates
01 January 2009 ->
Occupation or position held
Research Assistant Professor
Dates
01 September 2007 - 31 December 2008
Occupation or position held
Research assistant
Name and address of employer
Prof. Anna Erdei
Hungarian Academy of Sciences Subsidised Research Units at Eötvös Loránd University, Department of Immunology
1/C, Pázmány Péter s., H-1117 Budapest, Hungary
E-mail: anna.erdei@freemail.hu
Website: http://immunologia.elte.hu
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Dates
10 September 2004 - 31 July 2005
Occupation or position held
Visiting Scholar
Main activities and responsibilities
Mass-spectrometry
Name and address of employer
Prof. John D. Lambris
University of Pennsylvania, Protein Chemistry Laboratory
401 Stellar Chance, Philadelphia, PA 19104, USA
E-mail: lambris@mail.med.upenn.edu
Website:http://www.lambris.com/
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Dates
28 of May 2002 - 31 August 2002
Occupation or position held
Visiting Scholar
Name and address of employer
Prof. John D. Lambris
University of Pennsylvania, Protein Chemistry Laboratory
401 Stellar Chance, Philadelphia, PA 19104, USA
E-mail: lambris@mail.med.upenn.edu
Website:http://www.lambris.com/
Education and training
Dates
26 August 2003 -> 4 September 2008
Title of qualification awarded
PhD (Immunology)
Principal subjects / occupational skills covered
Immunolgy
Name and type of organisation providing education and training
Eötvös Loránd University
Faculty of Science, Department of Immunology
Budapest, Hungary
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Dates
06 September 2004 - 13 September 2004
Principal subjects / occupational skills covered
FEBS International Summer School on Immunology
Ionian Village, Western Peloponnese, Greece
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Dates
01 September 1998 - 23 June 2003
Title of qualification awarded
Biologist (MSc)
Principal subjects / occupational skills covered
Molecular Biology
Name and type of organisation providing education and training
Eötvös Loránd University, Faculty of Science
Budapest, Hungary
Personal skills and competences
Mother tongue
Hungarian
Other language(s)
English (C1)
German (B1)
Computer skills and competences
Computer operator certificate
Home page editing
Scientific results
Awards
2011 János Bolyai Scientific Award (Hungarian Academy of Sciences)
2010 Bio-Science Award
2009 Academic Young Scientist Award (Hungarian Academy of Sciences)
2008. The Scopus Award for Biochemistry
2007. Bio-Science Award
2003. Excellent Student of the Faculty Award
2003. National Student Research Council Award (3rd)
2002. University Student Research Council Award (1st)
Membership
Hungarian Society for Immunology
Hungarian Biochemical Society
Patent
WO2008007159
„Measurement of complement activation products on antigen arrays ”
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Publications

Papers:

  • Krisztián Papp, Péter Végh, Renáta Hóbor, Anna Erdei, József Prechl: “Characterization of factors influencing on-chip complement activation to optimize parallel measurement of antibody and complement proteins on antigen microarrays” J. Immunol Methods 2011 (Epub)
  • Zsuzsanna Szekeres, Melinda Herbáth, Zoltán Szittner, Krisztián Papp, Anna Erdei, József Prechl: “Modulation of the humoral immune response by targeting CD40 and FcγRII/III; delivery of soluble but not particulate antigen to CD40 enhances antibody responses with a Th1 bias” Molecular Immunology 2011.49:155-62
  • Zita Schneider, Judit Cervenak, Mária Baranyi, Krisztián Papp, József Prechl, Glória László, Anna Erdei, Imre Kacskovics: “Transgenic expression of bovine neonatal Fc receptor in mice boosts immune response and improves hybridoma production efficiency without any sign of autoimmunity.” Immunology Letters 2011. 137:62-9
  • Krisztián Papp, Péter Végh, Andrey Tchorbanov, Tchavdar Vassilev, Anna Erdei, József Prechl:“Progression of lupus-like disease drives the appearance of complement-activating IgG antibodies in MRL/lpr mice” Rheumatology 2010. 49:2273-80.
  • Stefanie Strobel, Miriam Zimmering, Krisztián Papp, József Prechl, Mihály Józsi: “Anti-factor B autoantibody in dense deposit disease” Molecular Immunology 2010. 47:1476–1483.
  • József Prechl, Krisztián Papp, Anna Erdei: Antigen microarrays: descriptive chemistry or functional immunomics? Trends in Immunology 2010. 31:133-137.
  • Nóra Terényi, Nándor Nagy, Krisztián Papp, József Prechl, Imre Oláh, Anna Erdei: “Transient decomplementation of mice delays onset of experimental autoimmune encephalomyelitis and impairs MOG-specific T cell response and autoantibody production” Molecular Immunology 2009. 47:57-63
  • Krisztián Papp, Péter Végh, József Prechl, Krisztina Kerekes, János Kovács, György Csikós, Zsuzsa Bajtay, Anna Erdei: “B lymphocytes and macrophages release cell membrane deposited C3-fragments on exosomes with T cell response-enhancing capacity” Molecular Immunology 2008. 45:2343–2351
  • Michael C. Schuster, Daniel Ricklin, Krisztián Papp, Kathleen S. Molnar, Stephen J. Coales, Yoshitomo Hamuro, Georgia Sfyroera, Hui Chen, Michael S. Winters, John D. Lambris: “Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry” Molecular Immunology 2008. 45:3142-3151
  • Krisztián Papp, Zsuzsanna Szekeres, Anna Erdei, József Prechl: “Two-dimensional immune profiles improve antigen microarray-based characterization of humoral immunity” Proteomics 2008. 8:2840-2848.
  • Krisztián Papp, Péter Végh, Kata Miklós, Julianna Németh, Klára Rásky, Ferenc Péterfy, Anna Erdei, József Prechl: Detection of complement activation on antigen microarrays generates functional antibody profiles and helps characterization of disease associated changes of the antibody repertoire Journal of Immunology 2008. 181:8162-8169
  • Krisztián Papp, Zsuzsanna Szekeres, Nóra Terenyi, Andrea Isaák, Anna Erdei, József Prechl: “On-chip complement activation adds an extra dimension to antigen microarrays” Molecular & Cellular Proteomics 2007. 6:133-140.
  • Dimitrios Mastellos, József Prechl, Glória László, Krisztián Papp, Eszter Oláh, Emelia Argyropoulos, Silvia Franchini, Ruxandra Tudoran, Maciej Markiewski, John D. Lambris, Anna Erdei: “Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays” Molecular Immunology 2004. 40:1213-21

Book chapter:

  • József Prechl, Eszter Molnár, Zsuzsanna Szekeres, Andrea Isaák, Krisztián Papp, Péter Balogh, Anna Erdei. “Murine CR1/2 targeted antigenized single-chain antibody fragments induce transient low affinity antibodies and negatively influence an ongoing immune response” Advances in Experimental Medicine and Biology, Current Topics in Innate Immunity, Springer New York 2007 vol. 598.

Oral presentations:

Signal and Signal Processing in the Immune System, 15-19 September 2007, Balatonöszöd, Hungary

  • Krisztián Papp, Péter Végh, József Prechl, Krisztina Kerekes, János Kovács, György Csikós, Zsuzsa Bajtay, Anna Erdei: “B lymphocytes and macrophages release cell membrane deposited C3 fragments on exosomes with T cell response enhancing capacity”

Abstracts at international conferences:

Signal and Signal Processing in the Immune System, 15-19 September 2007, Balatonöszöd, Hungary

  • Anna Erdei, Eszter Molnár, József Prechl, Krisztián Papp: “Novel roles of complement receptor CR1/2 on mouse T- and B lymphocytes”
  • Nóra Terényi, Krisztián Papp, Imre Oláh, József Prechl, Anna Erdei: “The effect of in vivo decomplementation in EAE, the mouse model of multiplex sclerosis”

XIth European meeting on Complement in Human Disease, 8-11 September 2007, Cardiff, UK

  • Krisztián Papp, József Prechl, Zsuzsanna Szekeres, Anna Erdei : “On-chip complement activation is a suitable technique for the simultaneous detection of the presence and complement activating properties of autoantibodies” Molecular Immunology 44 (2007) 3953
  • József Prechl, Krisztián Papp, Péter Végh, Anna Erdei: “On-chip complement activation for functional profiling of serum antibodies on antigen microarrays” Molecular Immunology 44 (2007) 3917

XXI International Complement Workshop, 22-26 October 2006, Beijing, China

  • John D. Lambris, Georgia Sfyroera, Michael Schuster, Hui Chen, Apostolia Tzekou, Krisztián Papp, Mike Winters, Virgil L. Woods: “Studies on the solvent accessibility of native C3 and its fragments, as analyzed by HDX-MS” Molecular Immunology Vol. 44, Issues 1-3, January 2007, Page 202

1st Joint Meeting of European National Societies of Immunology Under the auspices of EFIS, 2006 Paris, France

  • Krisztián Papp, József Prechl, Péter Végh, Anna Erdei: “Exosomes released by macrophages contain complement C3”

13th Symposium on Signals and Signali Processing in the Immune System, 2005 Balatonöszöd, Hungary

  • Krisztián Papp, József Prechl, Péter Végh, Anna Erdei: “Exosomes released by macrophages contain complement C3; an efficient way to remove cell surface bound C3 fragments?”

12th Symposium on Signals and Signaling Processing in the Immune System (EFIS) 2003 Sopron, Hungary

  • Eszter Molnár, József Prechl, Krisztián Papp, Dorottya Kövesdi, Anna Erdei: “The role of C3-binding receptors (CD21/CD35) in the survival and proliferation of murine B lymphocytes”

15th European Immunology Congress-EFIS 2003, Rhodes, Greece

  • Krisztián Papp, Glória László, József Prechl, Eszter Molnár, John D. Lambris, Anna Erdei : “Inhibition of Complement Activation by Monoclonal Antibodies to Mouse C3” Immunology Letters 2003, Vol. 87, (1-3) 41. (abstract in special issue)
  • Eszter Molnár, József Prechl, Andrea Isaák, Eszter Csomor, Krisztián Papp, Anna Erdei: “The Role of C3-Binding Receptors(CD21/CD35) in the Survival of Murine B Lymphocytes” Immunology Letters 2003, Vol. 87, (1-3) 117. (abstract in special issue)
  • József Prechl, Eszter Molnár, Andrea Isaák, Krisztián Papp, Anna Erdei: “Targeting Antigen to CR1/2 by Single-Chain Antibody Fragments Results in Low Affinity IgM Response Without the Induction of Memory Immunology” Letters 2003,Vol. 87, (1-3) 302. (abstact in special issue)

XIX. International Complement Workshop 2002, Palermo, Italy

  • József Prechl, Eszter Molnár, Andrea Isaák, Krisztián Papp, Anna Erdei: “Targeting antigen to CR1/2 by single-chain antibody fragments results in low affinity IgM response without the induction of memory”
  • Anna Erdei, Glória László, Eszter Oláh, József Prechl, Krisztián Papp, Eszter Csomor, Emelia Argyropoulos, Silvia Franchini,, Dimitrios Mastellos, John D. Lambris: “Monoclonal antibodies against mouse C3-fragments- a new repertoire of reagents targeting C3-mediated functions” International Immunopharmacology 2002 Vol.2 (9) 1327.